# Boosting the Boost: Mix‑and‑Match Covid Shots Shine*
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## Which combo packs the punch?*
| Vaccine order |
Antibody rise after first booster |
Antibody rise after second booster |
| CanSino + Sinovac (two doses) |
78‑fold boost × 2 weeks after the CanSino shot |
6.2‑fold boost with a second Sinovac dose |
| Sinovac + CanSino (one dose) |
25.7‑fold boost at 1‑2 month intervals |
15.2‑fold boost with another Sinovac dose |
## How the study was run*
Participants: ~300 healthy adults, ages 18‑59
Timing: CanSino boosters given 3‑6 months after a second Sinovac shot
Outcome: Neutralising antibody levels measured two weeks later
## Key take‑aways*
CanSino as the booster? Absolutely! It outshines Sinovac in anyone who got it after their first two Sinovac shots.
Mix‑and‑match works: Going from one Sinovac dose to a CanSino booster gives a massive 25.7‑fold spike—more than three times what a fit‑sir would see from dumping another Sinovac.
No direct protection data: The study didn’t test how well these combos stave off the virus or the Delta variant, so we’re still waiting for real‑world efficacy numbers.
China’s massive rollout: Over 1.4 billion Sinovac doses seen worldwide (≈¾ in China) and 69 % of the Chinese population fully vaccinated, with 2.1 billion doses administered by early September.
## What this means for you*
If your region offers these mix‑and‑match options, a CanSino booster on top of Sinovac may give you the strongest antibody boost yet—so go ahead, mix it up!
